3 Effectiveness of ECT - drug guide




Effectiveness of ECT




DEEPSAND562@AOL.COMSHOKU (LOSTBOYINNC) 2004-09-24 05:45:45

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15087991

J ECT. 2004 Mar;20(1):13-20. Related Articles, Links


Efficacy of ECT in depression: a meta-analytic review.

Pagnin D, de Queiroz V, Pini S, Cassano GB.

Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology.
University of Pisa, Italy. d.pagnin@psico.med.unipi.it

This study analyzed the efficacy of electroconvulsive therapy (ECT) in
depression by means a meta-analytic review of randomized controlled trials that
compared ECT with simulated ECT or placebo or antidepressant drugs and by a
complementary meta-analytic review of nonrandomized controlled trials that
compared ECT with antidepressants drugs. The review revealed a significant
superiority of ECT in all comparisons: ECT versus simulated ECT, ECT versus
placebo, ECT versus antidepressants in general, ECT versus TCAs and ECT versus
MAOIs. The nonrandomized controlled trials also revealed a significant
statistical difference in favor of ECT when confronted with antidepressants
drugs. Data analyzed suggest that ECT is a valid therapeutic tool for treatment
of depression, including severe and resistant forms.

Publication Types:
Meta-Analysis
Review
Review, Tutorial

PMID: 15087991 [PubMed - indexed for MEDLINE]


J ECT. 2004 Mar;20(1):13-20. Related Articles, Links


Efficacy of ECT in depression: a meta-analytic review.

Pagnin D, de Queiroz V, Pini S, Cassano GB.

Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology.
University of Pisa, Italy. d.pagnin@psico.med.unipi.it

This study analyzed the efficacy of electroconvulsive therapy (ECT) in
depression by means a meta-analytic review of randomized controlled trials that
compared ECT with simulated ECT or placebo or antidepressant drugs and by a
complementary meta-analytic review of nonrandomized controlled trials that
compared ECT with antidepressants drugs. The review revealed a significant
superiority of ECT in all comparisons: ECT versus simulated ECT, ECT versus
placebo, ECT versus antidepressants in general, ECT versus TCAs and ECT versus
MAOIs. The nonrandomized controlled trials also revealed a significant
statistical difference in favor of ECT when confronted with antidepressants
drugs. Data analyzed suggest that ECT is a valid therapeutic tool for treatment
of depression, including severe and resistant forms.

Publication Types:
Meta-Analysis
Review
Review, Tutorial

PMID: 15087991 [PubMed - indexed for MEDLINE]

Eric

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