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Effectiveness of ECT
2004-09-24 05:45:45
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15087991 J ECT. 2004 Mar;20(1):13-20. Related Articles, Links Efficacy of ECT in depression: a meta-analytic review. Pagnin D, de Queiroz V, Pini S, Cassano GB. Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology. University of Pisa, Italy. d.pagnin@psico.med.unipi.it This study analyzed the efficacy of electroconvulsive therapy (ECT) in depression by means a meta-analytic review of randomized controlled trials that compared ECT with simulated ECT or placebo or antidepressant drugs and by a complementary meta-analytic review of nonrandomized controlled trials that compared ECT with antidepressants drugs. The review revealed a significant superiority of ECT in all comparisons: ECT versus simulated ECT, ECT versus placebo, ECT versus antidepressants in general, ECT versus TCAs and ECT versus MAOIs. The nonrandomized controlled trials also revealed a significant statistical difference in favor of ECT when confronted with antidepressants drugs. Data analyzed suggest that ECT is a valid therapeutic tool for treatment of depression, including severe and resistant forms. Publication Types: Meta-Analysis Review Review, Tutorial PMID: 15087991 [PubMed - indexed for MEDLINE] J ECT. 2004 Mar;20(1):13-20. Related Articles, Links Efficacy of ECT in depression: a meta-analytic review. Pagnin D, de Queiroz V, Pini S, Cassano GB. Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology. University of Pisa, Italy. d.pagnin@psico.med.unipi.it This study analyzed the efficacy of electroconvulsive therapy (ECT) in depression by means a meta-analytic review of randomized controlled trials that compared ECT with simulated ECT or placebo or antidepressant drugs and by a complementary meta-analytic review of nonrandomized controlled trials that compared ECT with antidepressants drugs. The review revealed a significant superiority of ECT in all comparisons: ECT versus simulated ECT, ECT versus placebo, ECT versus antidepressants in general, ECT versus TCAs and ECT versus MAOIs. The nonrandomized controlled trials also revealed a significant statistical difference in favor of ECT when confronted with antidepressants drugs. Data analyzed suggest that ECT is a valid therapeutic tool for treatment of depression, including severe and resistant forms. Publication Types: Meta-Analysis Review Review, Tutorial PMID: 15087991 [PubMed - indexed for MEDLINE] Eric "My job is to reeducate the masses about severe mental illness. They must be made to learn, whether they want to or not." LostBoyinNC |
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