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GBL neurotoxic?
2004-02-14 03:27:22
This probably is total BS, but i've heard that GBL is neurotoxic
before it gets converted to GHB, is this true? I've also heard that GBL, just like GHB, is naturaly occuring in the body in small quantities. I hear a lot btw ;)
2004-02-14 12:36:35
P.A wrote:
> This probably is total BS, but i've heard that GBL is neurotoxic > before it gets converted to GHB, is this true? > > I've also heard that GBL, just like GHB, is naturaly occuring in the > body in small quantities. I hear a lot btw ;) north :-)
2004-02-14 17:42:24
P.A wrote:
> This probably is total BS, but i've heard that GBL is neurotoxic > before it gets converted to GHB, is this true? What isnt? Aspartame, booze, botulism..its just various degrees. shit man they chlorinate the water here. To live you have to burn the candle a little you know? though these people might want G to be a better outright poison http://ngin.tripod.com/010702b.htm > I've also heard that GBL, just like GHB, is naturaly occuring in the > body in small quantities. I hear a lot btw ;) It occurs in my body naturally in small quantities. Usually of Friday and Saturday nights :) In water its in equilibrium so yeah theres bound to be GBL molecules whizzing about in there naturally.
2004-02-14 10:15:09
mastermind
> P.A wrote: > > > This probably is total BS, but i've heard that GBL is neurotoxic > > before it gets converted to GHB, is this true? > > > > I've also heard that GBL, just like GHB, is naturaly occuring in the > > body in small quantities. I hear a lot btw ;) > hope you don't believe all what you read or hear up there in the cold > north :-) Nah, i dont, that's why i asked here. ;) I seached PubMed and found this article: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uidsu16800&dopt=Abstract "Injection of gamma-butyrolactone (GBL; 400 mg kg-1, i.p.) 5 min before and 55 min after the MDMA provided substantial protection." "There were few significant changes in rats given MDMA plus GBL, ondansetron or pentobarbitone." So it seems more likely that GBL is protective and not neurotoxic. I wonder what my friend will say about this??
2004-02-15 15:32:34
You really can't conclude that GBL is neuroprotective from that article...
MDMA does some weird things to the serotonin system which cause nerotoxicity. It is very likely that timing the GBL administration differently would yield very different results. /drdaz "P.A" news:bfef79a9.0402141015.15f92bd6@posting.google.com... > mastermind > > P.A wrote: > > > > > This probably is total BS, but i've heard that GBL is neurotoxic > > > before it gets converted to GHB, is this true? > > > > > > I've also heard that GBL, just like GHB, is naturaly occuring in the > > > body in small quantities. I hear a lot btw ;) > > hope you don't believe all what you read or hear up there in the cold > > north :-) > > Nah, i dont, that's why i asked here. ;) > > I seached PubMed and found this article: > > > > "Injection of gamma-butyrolactone (GBL; 400 mg kg-1, i.p.) 5 min > before and 55 min after the MDMA provided substantial protection." > > "There were few significant changes in rats given MDMA plus GBL, > ondansetron or pentobarbitone." > > So it seems more likely that GBL is protective and not neurotoxic. I > wonder what my friend will say about this??
2004-02-17 07:10:28
gbl NEUROtoxic? nope! none of the g's or bdo are.. the metabolic
acidosis it puts some 24/7 users may be perhaps be regarded toxic to the meat-part body (i.e. unless a meat-head yourself..) dawnrzr@yahoo.com (P.A) wrote in message news: > This probably is total BS, but i've heard that GBL is neurotoxic > before it gets converted to GHB, is this true? > > I've also heard that GBL, just like GHB, is naturaly occuring in the > body in small quantities. I hear a lot btw ;) |
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